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Design of smart GE11-PLGA/PEG-PLGA blend nanoparticulate platforms for parenteral administration of hydrophilic macromolecular drugs: synthesis, preparation and in vitro/ex vivo characterization.
Colzani, Barbara; Speranza, Giovanna; Dorati, Rossella; Conti, Bice; Modena, Tiziana; Bruni, Giovanna; Zagato, Elisa; Vermeulen, Lotte; Dakwar, George R; Braeckmans, Kevin; Genta, Ida.
Afiliação
  • Colzani B; Department of Drug Sciences, University of Pavia, 12, Viale Taramelli, 27100, Pavia, Italy.
  • Speranza G; Department of Chemistry, University of Milan, 19, Via Golgi, 20130, Milano, Italy.
  • Dorati R; Department of Drug Sciences, University of Pavia, 12, Viale Taramelli, 27100, Pavia, Italy.
  • Conti B; Department of Drug Sciences, University of Pavia, 12, Viale Taramelli, 27100, Pavia, Italy.
  • Modena T; Department of Drug Sciences, University of Pavia, 12, Viale Taramelli, 27100, Pavia, Italy.
  • Bruni G; Department of Chemistry, University of Pavia, 12, Viale Taramelli, 27100, Pavia, Italy.
  • Zagato E; Laboratory for General Biochemistry and Physical Pharmacy, Ghent University, Ghent Research Group on Nanomedicines, Harelbekestraat 72, 9000, Ghent, Belgium.
  • Vermeulen L; Laboratory for General Biochemistry and Physical Pharmacy, Ghent University, Ghent Research Group on Nanomedicines, Harelbekestraat 72, 9000, Ghent, Belgium.
  • Dakwar GR; Laboratory for General Biochemistry and Physical Pharmacy, Ghent University, Ghent Research Group on Nanomedicines, Harelbekestraat 72, 9000, Ghent, Belgium.
  • Braeckmans K; Laboratory for General Biochemistry and Physical Pharmacy, Ghent University, Ghent Research Group on Nanomedicines, Harelbekestraat 72, 9000, Ghent, Belgium.
  • Genta I; Department of Drug Sciences, University of Pavia, 12, Viale Taramelli, 27100, Pavia, Italy. Electronic address: ida.genta@unipv.it.
Int J Pharm ; 511(2): 1112-23, 2016 Sep 25.
Article em En | MEDLINE | ID: mdl-27511710
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Polietilenoglicóis / Ácido Poliglicólico / Desenho de Fármacos / Ácido Láctico / Nanopartículas / Interações Hidrofóbicas e Hidrofílicas Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Polietilenoglicóis / Ácido Poliglicólico / Desenho de Fármacos / Ácido Láctico / Nanopartículas / Interações Hidrofóbicas e Hidrofílicas Idioma: En Ano de publicação: 2016 Tipo de documento: Article