A focused compound screen highlights the significance of epidermal growth factor receptor signalling in chordoma pathogenesis.

Ghaly, Mira; Seelemann, Corin; Jahani-Asl, Arezu

Ghaly, Mira; Seelemann, Corin; Jahani-Asl, Arezu.

Afiliação

Ghaly M; Department of Oncology, Faculty of Medicine, McGill University and Lady Davis Medical Research Institute, Jewish General Hospital, Montreal, Quebec, Canada.
Seelemann C; Department of Oncology, Faculty of Medicine, McGill University and Lady Davis Medical Research Institute, Jewish General Hospital, Montreal, Quebec, Canada.
Jahani-Asl A; Department of Oncology, Faculty of Medicine, McGill University and Lady Davis Medical Research Institute, Jewish General Hospital, Montreal, Quebec, Canada.

J Pathol ; 240(4): 381-383, 2016 12.

Article em En | MEDLINE | ID: mdl-27538356

Assuntos

Cordoma/tratamento farmacológico; Receptores ErbB/antagonistas & inibidores; Antineoplásicos/farmacologia; Humanos; Recidiva Local de Neoplasia/tratamento farmacológico; Reino Unido

Palavras-chave

EGFR inhibitors; MET inhibitors; chordoma; compound drug screen; crizotinib; met; sapitinib

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cordoma / Receptores ErbB Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cordoma / Receptores ErbB Idioma: En Ano de publicação: 2016 Tipo de documento: Article