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Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models.
Sanchez-Martinez, Alvaro; Beavan, Michelle; Gegg, Matthew E; Chau, Kai-Yin; Whitworth, Alexander J; Schapira, Anthony H V.
Afiliação
  • Sanchez-Martinez A; Department of Biomedical Sciences, University of Sheffield, Sheffield, S10 2TN, UK.
  • Beavan M; Medical Research Council Mitochondrial Biology Unit, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.
  • Gegg ME; Department of Clinical Neuroscience, Institute of Neurology, University College London, London NW3 2PF, UK.
  • Chau KY; Department of Clinical Neuroscience, Institute of Neurology, University College London, London NW3 2PF, UK.
  • Whitworth AJ; Department of Clinical Neuroscience, Institute of Neurology, University College London, London NW3 2PF, UK.
  • Schapira AH; Department of Biomedical Sciences, University of Sheffield, Sheffield, S10 2TN, UK.
Sci Rep ; 6: 31380, 2016 08 19.
Article em En | MEDLINE | ID: mdl-27539639
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Chaperonas Moleculares / Glucosilceramidase / Mutação Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Chaperonas Moleculares / Glucosilceramidase / Mutação Idioma: En Ano de publicação: 2016 Tipo de documento: Article