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Refolding of Aggregation-Prone ScFv Antibody Fragments Assisted by Hydrophobically Modified Poly(sodium acrylate) Derivatives.
Martin, Nicolas; Costa, Narciso; Wien, Frank; Winnik, Françoise M; Ortega, Céline; Herbet, Amaury; Boquet, Didier; Tribet, Christophe.
Afiliação
  • Martin N; Ecole normale supérieure, PSL Research University, UPMC Univ Paris 06, CNRS, Département de Chimie, PASTEUR, 24, rue Lhomond, 75005, Paris, France.
  • Costa N; Sorbonne Universités, UPMC Univ Paris 06, ENS, CNRS, PASTEUR, 75005, Paris, France.
  • Wien F; CEA, iBiTecS, SPI, Laboratoire d'Ingénierie des Anticorps pour la Santé (LIAS), Bt. 136, CEA Saclay, F-91191, Gif sur Yvette, France.
  • Winnik FM; Synchrotron Soleil, Saint-Aubin, F-91192, Gif-sur-Yvette, France.
  • Ortega C; Department of Chemistry, Faculty of Pharmacy, Université de Montréal, CP 6128 Succursale Centre Ville, Montréal, QC, H3C 3J7, Canada.
  • Herbet A; World Premier Initiative (WPI) International Research Center Initiative, International Center for Materials Nanoarchitectonics (MANA) and National Institute for Materials Science (NIMS) 1-1Namiki, Tsukuba, 305-0044, Japan.
  • Boquet D; Department of Chemistry and Faculty of Pharmacy, University of Helsinki, Helsinki, FI, 00014, Finland.
  • Tribet C; CEA, iBiTecS, SPI, Laboratoire d'Ingénierie des Anticorps pour la Santé (LIAS), Bt. 136, CEA Saclay, F-91191, Gif sur Yvette, France.
Macromol Biosci ; 17(2)2017 02.
Article em En | MEDLINE | ID: mdl-27548824
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resinas Acrílicas / Dobramento de Proteína / Anticorpos de Cadeia Única / Interações Hidrofóbicas e Hidrofílicas / Agregados Proteicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resinas Acrílicas / Dobramento de Proteína / Anticorpos de Cadeia Única / Interações Hidrofóbicas e Hidrofílicas / Agregados Proteicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article