The potential impact of bone tissue engineering in the clinic.
Regen Med
; 11(6): 571-87, 2016 09.
Article
em En
| MEDLINE
| ID: mdl-27549369
ABSTRACT
Bone tissue engineering (BTE) intends to restore structural support for movement and mineral homeostasis, and assist in hematopoiesis and the protective functions of bone in traumatic, degenerative, cancer, or congenital malformation. While much effort has been put into BTE, very little of this research has been translated to the clinic. In this review, we discuss current regenerative medicine and restorative strategies that utilize tissue engineering approaches to address bone defects within a clinical setting. These approaches involve the primary components of tissue engineering cells, growth factors and biomaterials discussed briefly in light of their clinical relevance. This review also presents upcoming advanced approaches for BTE applications and suggests a probable workpath for translation from the laboratory to the clinic.
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Base de dados:
MEDLINE
Assunto principal:
Osso e Ossos
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Doenças Ósseas
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Regeneração Óssea
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Engenharia Tecidual
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article