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Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors.
Singh, Anju; Venkannagari, Sreedhar; Oh, Kyu H; Zhang, Ya-Qin; Rohde, Jason M; Liu, Li; Nimmagadda, Sridhar; Sudini, Kuladeep; Brimacombe, Kyle R; Gajghate, Sachin; Ma, Jinfang; Wang, Amy; Xu, Xin; Shahane, Sampada A; Xia, Menghang; Woo, Juhyung; Mensah, George A; Wang, Zhibin; Ferrer, Marc; Gabrielson, Edward; Li, Zhuyin; Rastinejad, Fraydoon; Shen, Min; Boxer, Matthew B; Biswal, Shyam.
Afiliação
  • Singh A; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States.
  • Venkannagari S; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States.
  • Oh KH; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States.
  • Zhang YQ; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Rohde JM; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Liu L; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Nimmagadda S; Departments of Radiology and Oncology, School of Medicine, Johns Hopkins University , Baltimore, Maryland 21205, United States.
  • Sudini K; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States.
  • Brimacombe KR; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Gajghate S; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States.
  • Ma J; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States.
  • Wang A; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Xu X; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Shahane SA; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Xia M; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Woo J; Department of Oncology, School of Medicine, Johns Hopkins University , Baltimore, Maryland 21205, United States.
  • Mensah GA; Department of Pharmaceutical Sciences, Massachusetts College of Pharmacy and Health Sciences , Worcester, Massachusetts 01608, United States.
  • Wang Z; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States.
  • Ferrer M; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Gabrielson E; Department of Oncology, School of Medicine, Johns Hopkins University , Baltimore, Maryland 21205, United States.
  • Li Z; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Rastinejad F; Metabolic Signaling and Disease Program, Sanford-Burnham Medical Research Institute , Orlando, Florida 32827, United States.
  • Shen M; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Boxer MB; National Center for Advancing Translational Sciences, National Institutes of Health , Rockville, Maryland 20850, United States.
  • Biswal S; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University , Baltimore, Maryland 21205, United States.
ACS Chem Biol ; 11(11): 3214-3225, 2016 11 18.
Article em En | MEDLINE | ID: mdl-27552339
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Resistencia a Medicamentos Antineoplásicos / Fator 2 Relacionado a NF-E2 / Proteína 1 Associada a ECH Semelhante a Kelch / Neoplasias Pulmonares Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Resistencia a Medicamentos Antineoplásicos / Fator 2 Relacionado a NF-E2 / Proteína 1 Associada a ECH Semelhante a Kelch / Neoplasias Pulmonares Idioma: En Ano de publicação: 2016 Tipo de documento: Article