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Effect of LED photobiomodulation on fluorescent light induced changes in cellular ATPases and Cytochrome c oxidase activity in Wistar rat.
A, Ahamed Basha; C, Mathangi D; R, Shyamala.
Afiliação
  • A AB; Department of Physiology, Chettinad Hospital and Research Institute, Rajiv Gandhi Salai, Kelambakkam, Chennai, 603103, India. drahamedbasha@gmail.com.
  • C MD; Department of Physiology, Chettinad Hospital and Research Institute, Rajiv Gandhi Salai, Kelambakkam, Chennai, 603103, India.
  • R S; Department of Physiology, Chettinad Hospital and Research Institute, Rajiv Gandhi Salai, Kelambakkam, Chennai, 603103, India.
Lasers Med Sci ; 31(9): 1803-1809, 2016 Dec.
Article em En | MEDLINE | ID: mdl-27562504
BACKGROUND: Fluorescent light exposure at night alters cellular enzyme activities resulting in health defects. Studies have demonstrated that light emitting diode photobiomodulation enhances cellular enzyme activities. OBJECTIVE: The objectives of this study are to evaluate the effects of fluorescent light induced changes in cellular enzymes and to assess the protective role of pre exposure to 670 nm LED in rat model. METHODS: Male Wistar albino rats were divided into 10 groups of 6 animals each based on duration of exposure (1, 15, and 30 days) and exposure regimen (cage control, exposure to fluorescent light [1800 lx], LED preexposure followed by fluorescent light exposure and only LED exposure). Na+-K+ ATPase, Ca2+ ATPase, and cytochrome c oxidase of the brain, heart, kidney, liver, and skeletal muscle were assayed. RESULTS: Animals of the fluorescent light exposure group showed a significant reduction in Na+-K+ ATPase and Ca2+ ATPase activities in 1 and 15 days and their increase in animals of 30-day group in most of the regions studied. Cytochrome c oxidase showed increase in their level at all the time points assessed in most of the tissues. LED light preexposure showed a significant enhancement in the degree of increase in the enzyme activities in almost all the tissues and at all the time points assessed. CONCLUSIONS: This study demonstrates the protective effect of 670 nm LED pre exposure on cellular enzymes against fluorescent light induced change.
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Base de dados: MEDLINE Assunto principal: Terapia com Luz de Baixa Intensidade / Luz Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Terapia com Luz de Baixa Intensidade / Luz Idioma: En Ano de publicação: 2016 Tipo de documento: Article