Matrine Exerts a Strong Anti-Arthritic Effect on Type II Collagen-Induced Arthritis in Rats by Inhibiting Inflammatory Responses.

Pu, Jiang; Fang, Fan-Fu; Li, Xiu-Qing; Shu, Zhi-Heng; Jiang, Yi-Ping; Han, Ting; Peng, Wei; Zheng, Cheng-Jian

Pu, Jiang; Fang, Fan-Fu; Li, Xiu-Qing; Shu, Zhi-Heng; Jiang, Yi-Ping; Han, Ting; Peng, Wei; Zheng, Cheng-Jian.

Afiliação

Pu J; Administrative Office, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai 200433, China. pujiang0408@163.com.
Fang FF; Department of Rehabilitation, Changhai Hospital of TCM, Second Military Medical University, Shanghai 200433, China. fangfanfu@126.com.
Li XQ; Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China. liuxiuqing@126.com.
Shu ZH; Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China. 13817760547@163.com.
Jiang YP; Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China. msjyp@163.com.
Han T; Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China. than927@163.com.
Peng W; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China. pengwei002@126.com.
Zheng CJ; Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China. zhengchengjian1984@126.com.

Int J Mol Sci ; 17(9)2016 Aug 26.

Article em En | MEDLINE | ID: mdl-27571073

Assuntos

Alcaloides/uso terapêutico; Artrite Experimental/tratamento farmacológico; Colágeno Tipo II/toxicidade; Inflamação/tratamento farmacológico; Quinolizinas/uso terapêutico; Alcaloides/química; Animais; Artrite Experimental/induzido quimicamente; Artrite Experimental/imunologia; Inflamação/sangue; Interleucina-10/sangue; Interleucina-17/sangue; Interleucina-6/sangue; Interleucina-8/sangue; Masculino; Metaloproteinase 2 da Matriz/sangue; Metaloproteinase 3 da Matriz/sangue; Metaloproteinase 9 da Matriz/sangue; Quinolizinas/química; Ratos; Ratos Sprague-Dawley; Sophora/química; Matrinas

Palavras-chave

Sophora flavescens; anti-arthritic effect; matrine; rheumatoid arthritis; type II collagen

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Experimental / Quinolizinas / Colágeno Tipo II / Alcaloides / Inflamação Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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