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MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma.
Fabian, Johannes; Opitz, Desirée; Althoff, Kristina; Lodrini, Marco; Hero, Barbara; Volland, Ruth; Beckers, Anneleen; de Preter, Katleen; Decock, Anneleen; Patil, Nitin; Abba, Mohammed; Kopp-Schneider, Annette; Astrahantseff, Kathy; Wünschel, Jasmin; Pfeil, Sebastian; Ercu, Maria; Künkele, Annette; Hu, Jamie; Thole, Theresa; Schweizer, Leonille; Mechtersheimer, Gunhild; Carter, Daniel; Cheung, Belamy B; Popanda, Odilia; von Deimling, Andreas; Koster, Jan; Versteeg, Rogier; Schwab, Manfred; Marshall, Glenn M; Speleman, Frank; Erb, Ulrike; Zoeller, Margot; Allgayer, Heike; Simon, Thorsten; Fischer, Matthias; Kulozik, Andreas E; Eggert, Angelika; Witt, Olaf; Schulte, Johannes H; Deubzer, Hedwig E.
Afiliação
  • Fabian J; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ) and German Consortium for Translational Cancer Research (DKTK), INF, Heidelberg, Germany.
  • Opitz D; Phenex Pharmaceuticals AG, Waldhofer Straße, Heidelberg, Germany.
  • Althoff K; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ) and German Consortium for Translational Cancer Research (DKTK), INF, Heidelberg, Germany.
  • Lodrini M; Department of Pediatric Hematology and Oncology, University Children's Hospital Essen, Essen, Germany.
  • Hero B; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ) and German Consortium for Translational Cancer Research (DKTK), INF, Heidelberg, Germany.
  • Volland R; Department of Pediatric Hematology, Oncology and SCT, Charité - University Hospital Berlin, Campus Virchow-Klinikum, Berlin, Germany.
  • Beckers A; Department of Pediatric Hematology and Oncology, University of Cologne, Cologne, Germany.
  • de Preter K; Department of Pediatric Hematology and Oncology, University of Cologne, Cologne, Germany.
  • Decock A; Center for Medical Genetics Ghent, Ghent University, De Pintelaan, Ghent, Belgium.
  • Patil N; Cancer Research Institute Ghent, De Pintelaan, Ghent, Belgium.
  • Abba M; Center for Medical Genetics Ghent, Ghent University, De Pintelaan, Ghent, Belgium.
  • Kopp-Schneider A; Cancer Research Institute Ghent, De Pintelaan, Ghent, Belgium.
  • Astrahantseff K; Center for Medical Genetics Ghent, Ghent University, De Pintelaan, Ghent, Belgium.
  • Wünschel J; Cancer Research Institute Ghent, De Pintelaan, Ghent, Belgium.
  • Pfeil S; Department of Experimental Surgery, Medical Faculty Mannheim, University of Heidelberg, Centre for Biomedicine and Medical Technology, Mannheim, Germany.
  • Ercu M; Department of Experimental Surgery, Medical Faculty Mannheim, University of Heidelberg, Centre for Biomedicine and Medical Technology, Mannheim, Germany.
  • Künkele A; Department of Biostatistics, German Cancer Research Center (DKFZ), INF, Heidelberg, Germany.
  • Hu J; Department of Pediatric Hematology, Oncology and SCT, Charité - University Hospital Berlin, Campus Virchow-Klinikum, Berlin, Germany.
  • Thole T; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ) and German Consortium for Translational Cancer Research (DKTK), INF, Heidelberg, Germany.
  • Schweizer L; Department of Pediatric Hematology, Oncology and SCT, Charité - University Hospital Berlin, Campus Virchow-Klinikum, Berlin, Germany.
  • Mechtersheimer G; Department of Pediatric Hematology, Oncology and SCT, Charité - University Hospital Berlin, Campus Virchow-Klinikum, Berlin, Germany.
  • Carter D; Department of Pediatric Hematology, Oncology and SCT, Charité - University Hospital Berlin, Campus Virchow-Klinikum, Berlin, Germany.
  • Cheung BB; Department of Pediatric Hematology, Oncology and SCT, Charité - University Hospital Berlin, Campus Virchow-Klinikum, Berlin, Germany.
  • Popanda O; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ) and German Consortium for Translational Cancer Research (DKTK), INF, Heidelberg, Germany.
  • von Deimling A; Yale University, New Haven, CT.
  • Koster J; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ) and German Consortium for Translational Cancer Research (DKTK), INF, Heidelberg, Germany.
  • Versteeg R; Department of Pediatric Hematology, Oncology and SCT, Charité - University Hospital Berlin, Campus Virchow-Klinikum, Berlin, Germany.
  • Schwab M; Department of Neuropathology, University of Heidelberg, INF, Heidelberg, Germany.
  • Marshall GM; Department of Pathology, University of Heidelberg, INF, Heidelberg, Germany.
  • Speleman F; Children's Cancer Institute, UNSW, Randwick, NSW, Australia.
  • Erb U; Children's Cancer Institute, UNSW, Randwick, NSW, Australia.
  • Zoeller M; Division of Epigenomics and Cancer Risk Factors, DKFZ, INF, Heidelberg, Germany.
  • Allgayer H; Department of Neuropathology, University of Heidelberg, INF, Heidelberg, Germany.
  • Simon T; Clinical Cooperation Unit Neuropathology, DKFZ, INF, Heidelberg, Germany.
  • Fischer M; Department of Oncogenomics and Emma Children's Hospital, Academic Medical Center, University of Amster- dam, Meibergdreef, Amsterdam, the Netherlands.
  • Kulozik AE; Department of Oncogenomics and Emma Children's Hospital, Academic Medical Center, University of Amster- dam, Meibergdreef, Amsterdam, the Netherlands.
  • Eggert A; Neuroblastoma Genetics, DKFZ, INF, Heidelberg, Germany.
  • Witt O; Children's Cancer Institute, UNSW, Randwick, NSW, Australia.
  • Schulte JH; Kids Cancer Centre, Sydney Children's Hospital Randwick, Randwick, NSW, Australia.
  • Deubzer HE; Center for Medical Genetics Ghent, Ghent University, De Pintelaan, Ghent, Belgium.
Oncotarget ; 7(41): 66344-66359, 2016 10 11.
Article em En | MEDLINE | ID: mdl-27572323
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Tetraspanina 29 / Proteína Proto-Oncogênica N-Myc / Histona Desacetilases / Neuroblastoma Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Tetraspanina 29 / Proteína Proto-Oncogênica N-Myc / Histona Desacetilases / Neuroblastoma Idioma: En Ano de publicação: 2016 Tipo de documento: Article