Changes in Urinary Microbiome Populations Correlate in Kidney Transplants With Interstitial Fibrosis and Tubular Atrophy Documented in Early Surveillance Biopsies.

Modena, B D; Milam, R; Harrison, F; Cheeseman, J A; Abecassis, M M; Friedewald, J J; Kirk, A D; Salomon, D R

Modena, B D; Milam, R; Harrison, F; Cheeseman, J A; Abecassis, M M; Friedewald, J J; Kirk, A D; Salomon, D R.

Afiliação

Modena BD; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA.
Milam R; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA.
Harrison F; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA.
Cheeseman JA; Department of Surgery, Duke University, Durham, NC.
Abecassis MM; Northwestern Comprehensive Transplant Center, Northwestern University, Chicago, IL.
Friedewald JJ; Northwestern Comprehensive Transplant Center, Northwestern University, Chicago, IL.
Kirk AD; Department of Surgery, Duke University, Durham, NC.
Salomon DR; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA.

Am J Transplant ; 17(3): 712-723, 2017 03.

Article em En | MEDLINE | ID: mdl-27597148

Assuntos

Atrofia/urina; Biomarcadores/urina; Fibrose/urina; Rejeição de Enxerto/urina; Transplante de Rim/efeitos adversos; Túbulos Renais/patologia; Doenças Pulmonares Intersticiais/urina; Microbiota/genética; Atrofia/etiologia; Biópsia; Estudos de Casos e Controles; Feminino; Fibrose/etiologia; Seguimentos; Taxa de Filtração Glomerular; Rejeição de Enxerto/etiologia; Rejeição de Enxerto/patologia; Sobrevivência de Enxerto; Humanos; Falência Renal Crônica/complicações; Falência Renal Crônica/cirurgia; Testes de Função Renal; Túbulos Renais/metabolismo; Doenças Pulmonares Intersticiais/etiologia; Masculino; Pessoa de Meia-Idade; Prognóstico; RNA Ribossômico 16S/genética; Fatores de Risco

Palavras-chave

basic (laboratory) research/science; clinical research/practice; immunobiology; immunosuppression/immune modulation; interstitial fibrosis and tubular atrophy; kidney (allograft) function/dysfunction; kidney transplantation/nephrology; microbiomics; rejection: chronic; tissue injury and repair

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Atrofia / Fibrose / Biomarcadores / Transplante de Rim / Doenças Pulmonares Intersticiais / Microbiota / Rejeição de Enxerto / Túbulos Renais Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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