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UVR protection influences fructosamine level after sun exposure of healthy adults.
Mianowska, Beata; Narbutt, Joanna; Young, Antony Richard; Fendler, Wojciech; Malachowska, Beata; Mlynarski, Wojciech; Lesiak, Aleksandra.
Afiliação
  • Mianowska B; Department of Paediatrics, Oncology, Haematology and Diabetology, Medical University of Lodz, Lodz, Poland.
  • Narbutt J; Department of Dermatology, Medical University of Lodz, Lodz, Poland.
  • Young AR; St John's Institute of Dermatology, King's College London, London, UK.
  • Fendler W; Department of Paediatrics, Oncology, Haematology and Diabetology, Medical University of Lodz, Lodz, Poland.
  • Malachowska B; Department of Paediatrics, Oncology, Haematology and Diabetology, Medical University of Lodz, Lodz, Poland.
  • Mlynarski W; Department of Paediatrics, Oncology, Haematology and Diabetology, Medical University of Lodz, Lodz, Poland.
  • Lesiak A; Department of Dermatology, Medical University of Lodz, Lodz, Poland.
Photodermatol Photoimmunol Photomed ; 32(5-6): 296-303, 2016 Sep.
Article em En | MEDLINE | ID: mdl-27623292
BACKGROUND: Seasonal variation in glycated hemoglobin levels has been observed, and sun exposure has been considered as one of the factors associated with this relationship. Fructosamine is a short-time marker of blood protein glycation. AIM: We investigated the effect of seven days of sunbathing on blood fructosamine concentration in healthy volunteers using different ultraviolet radiation (UVR) protections. MATERIALS AND METHODS: Participants were assigned to one of three groups: group A - used a UVA and UVB absorbing sunscreen (N = 15), group B - used a UVB absorbing sunscreen (N = 18), and group C - followed uncontrolled sun protection habits (N = 22). RESULTS: Overall, the fructosamine concentration did not change after sun exposure (baseline 248.8 µmol/l, 25-75%: 238.5 to 258.8 µmol/l vs. after 247.3 µmol/l, 25-75%: 234.9 to 261.8 µmol/l, P = 0.6637). Median change of fructosamine differed significantly between groups (A: -1.90 µmol/l, 25-75%: -17.10 to 1.80 µmol/l vs. B: -3.80 µmol/l, 25-75%: -18.50 to 2.40 µmol/l vs. C: +4.05 µmol/l, 25-75%: -3.20 to 22.0 µmol/l; one-way ANOVAP = 0.0277). After age adjustment and combining groups A and B, the difference in change of fructosamine concentration was statistically significant between groups A + B (decrease) vs. group C (increase, P = 0.0193). CONCLUSION: Appropriate sunscreen use during sunbathing resulted in decreased fructosamine concentrations, while inadequate UVR protection resulted in its increase.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Luz Solar / Protetores Solares / Frutosamina Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Luz Solar / Protetores Solares / Frutosamina Idioma: En Ano de publicação: 2016 Tipo de documento: Article