Splenic marginal zone lymphoma: An indolent malignancy leading to the development of neurolymphomatosis.
Muscle Nerve
; 55(3): 440-444, 2017 03.
Article
em En
| MEDLINE
| ID: mdl-27625159
ABSTRACT
INTRODUCTION:
Acute neuropathic pain and weakness with a sensory level in a patient with a history of lymphoma has a broad differential diagnosis. Evaluation of such a presentation often includes MRI, neurophysiologic studies, and cerebrospinal fluid evaluation. We report a patient with splenic marginal zone lymphoma who developed acute weakness, sensory loss, and neuropathic pain due to neurolymphomatosis.METHODS:
Clinical evaluation, MRI of the lumbar spine, cerebrospinal fluid evaluation, electrodiagnostic (EDx) studies, and biopsy of a dorsal nerve root were undertaken.RESULTS:
EDx studies were consistent with an acute, acquired demyelinating sensorimotor polyradiculoneuropathy. Treatment with intravenous immunoglobulin and plasma exchange did not lead to clinical improvement. Ultimately, biopsy of a dorsal nerve root was performed and revealed neurolymphomatosis.CONCLUSION:
This case emphasizes that, when it can be performed safely, biopsy for suspected neurolymphomatosis is imperative for appropriate diagnosis and treatment. Muscle Nerve 55 440-444, 2017.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Cauda Equina
/
Doença de Marek
/
Linfoma
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article