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A gene expression signature of retinoblastoma loss-of-function is a predictive biomarker of resistance to palbociclib in breast cancer cell lines and is prognostic in patients with ER positive early breast cancer.
Malorni, Luca; Piazza, Silvano; Ciani, Yari; Guarducci, Cristina; Bonechi, Martina; Biagioni, Chiara; Hart, Christopher D; Verardo, Roberto; Di Leo, Angelo; Migliaccio, Ilenia.
Afiliação
  • Malorni L; "Sandro Pitigliani" Translational Research Unit, Hospital of Prato-AUSL Toscana Centro, Istituto Toscano Tumori, Prato, Italy.
  • Piazza S; "Sandro Pitigliani" Medical Oncology Department, Hospital of Prato-AUSL Toscana Centro, Istituto Toscano Tumori, Prato, Italy.
  • Ciani Y; Laboratorio Nazionale CIB (LNCIB), Area Science Park, and Functional Genomics & Bioinformatics Units, Trieste, Italy.
  • Guarducci C; Bioinformatics Core Facility, Centre for Integrative Biology (CIBIO), University of Trento, Trento, Italy.
  • Bonechi M; Laboratorio Nazionale CIB (LNCIB), Area Science Park, and Functional Genomics & Bioinformatics Units, Trieste, Italy.
  • Biagioni C; "Sandro Pitigliani" Translational Research Unit, Hospital of Prato-AUSL Toscana Centro, Istituto Toscano Tumori, Prato, Italy.
  • Hart CD; "Sandro Pitigliani" Translational Research Unit, Hospital of Prato-AUSL Toscana Centro, Istituto Toscano Tumori, Prato, Italy.
  • Verardo R; "Sandro Pitigliani" Translational Research Unit, Hospital of Prato-AUSL Toscana Centro, Istituto Toscano Tumori, Prato, Italy.
  • Di Leo A; "Sandro Pitigliani" Medical Oncology Department, Hospital of Prato-AUSL Toscana Centro, Istituto Toscano Tumori, Prato, Italy.
  • Migliaccio I; "Sandro Pitigliani" Medical Oncology Department, Hospital of Prato-AUSL Toscana Centro, Istituto Toscano Tumori, Prato, Italy.
Oncotarget ; 7(42): 68012-68022, 2016 09 13.
Article em En | MEDLINE | ID: mdl-27634906
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Piridinas / Neoplasias da Mama / Biomarcadores / Proteína do Retinoblastoma / Antineoplásicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Piridinas / Neoplasias da Mama / Biomarcadores / Proteína do Retinoblastoma / Antineoplásicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article