The Streptomyces K15 DD-peptidase/penicillin-binding protein. Active site and sequence of the N-terminal region.
Biochem J
; 260(2): 601-4, 1989 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-2764892
ABSTRACT
The N-terminal region of the Streptomyces K15 DD-peptidase/penicillin-binding protein shows high homology with that of other penicillin-interactive proteins or domains. The active-site serine residue of the conserved tetrad Ser-Xaa-Xaa-Lys occurs at position 35. There is no indication for the presence of a signal peptide or an N-terminal hydrophobic sequence, suggesting that the Streptomyces K15 enzyme is probably anchored to the membrane by a C-terminal peptide segment.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Streptomyces
/
Proteínas de Bactérias
/
Muramilpentapeptídeo Carboxipeptidase
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Proteínas de Transporte
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Peptidil Transferases
/
Hexosiltransferases
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article