Autologous intrauterine transfusion in a case of anti-U.
Transfusion
; 56(12): 3029-3032, 2016 12.
Article
em En
| MEDLINE
| ID: mdl-27664105
ABSTRACT
BACKGROUND:
Minor red blood cell antibodies are becoming a more common cause of hemolytic disease of the newborn. Anti-U are a rare alloantibody found almost exclusively in people of black descent. There is limited experience to guide the management of pregnancies complicated by anti-U. Furthermore, there is often no suitable cross-matched blood available for transfusion of a patient with anti-U. CASE REPORT A 21-year-old P0G1 presented at 25 weeks' gestation with D- disease in pregnancy. She had a significant indirect antiglobulin test titer of 512. Anti-U were identified and no suitable cross-matched blood was available. Maternal blood was prepared for autologous intrauterine fetal transfusion. Two such transfusions were performed.RESULTS:
A healthy fetus delivered at 32 weeks that did not require phototherapy or an exchange transfusion.CONCLUSION:
Autologous transfusion of prepared maternal blood provides a safe option for intrauterine fetal therapy in pregnancies complicated by rare alloantibodies.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transfusão de Sangue Intrauterina
/
Eritroblastose Fetal
/
Isoanticorpos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article