[Actualities in the management of primary myelofibrosis]. / Aktualitások a primer myelofibrosis ellátásában.
Orv Hetil
; 157(39): 1547-1556, 2016 09.
Article
em Hu
| MEDLINE
| ID: mdl-27667294
ABSTRACT
Primary myelofibrosis is one of the Philadelphia negative chronic myeloproliferative neoplasms. It is a rare disease featured by cytopenias and hepatosplenomegaly. Although the etiology of the disease is still unknown, our knowledge about its pathology and prognosis has been improving in the last few years. Furthermore, the JAK2 inhibitor ruxolitinib has become available in Hungary since 2015. Beside its high efficacy in spleen volume and in reduction of myelofibrosis-associated symptoms, this novel therapy also exerts a disease-modifying effect and, therefore, ruxolitinib may improve the life expectancy too. Treatment approach of myelofibrosis has been changed these years, which gives a reason for this summary. Orv. Hetil., 2016, 157(39), 1547-1556.
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MEDLINE
Idioma:
Hu
Ano de publicação:
2016
Tipo de documento:
Article