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Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs tumour growth in human colorectal cancer.
Borovski, Tijana; Vellinga, Thomas T; Laoukili, Jamila; Santo, Evan E; Fatrai, Szabolcs; van Schelven, Susanne; Verheem, Andre; Marvin, Dieuwke L; Ubink, Inge; Borel Rinkes, Inne H M; Kranenburg, Onno.
Afiliação
  • Borovski T; Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Vellinga TT; Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Laoukili J; Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Santo EE; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York City, New York, USA.
  • Fatrai S; Department of Hematology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • van Schelven S; Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Verheem A; Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Marvin DL; Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Ubink I; Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Borel Rinkes IHM; Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Kranenburg O; Cancer Center, University Medical Center Utrecht, Utrecht, The Netherlands.
Gut ; 66(6): 1106-1115, 2017 06.
Article em En | MEDLINE | ID: mdl-27670374
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Adenocarcinoma / Proteínas Proto-Oncogênicas c-raf Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Adenocarcinoma / Proteínas Proto-Oncogênicas c-raf Idioma: En Ano de publicação: 2017 Tipo de documento: Article