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Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor.
Kaye, Joel; Piryatinsky, Victor; Birnberg, Tal; Hingaly, Tal; Raymond, Emanuel; Kashi, Rina; Amit-Romach, Einat; Caballero, Ignacio S; Towfic, Fadi; Ator, Mark A; Rubinstein, Efrat; Laifenfeld, Daphna; Orbach, Aric; Shinar, Doron; Marantz, Yael; Grossman, Iris; Knappertz, Volker; Hayden, Michael R; Laufer, Ralph.
Afiliação
  • Kaye J; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel; joel.kaye@teva.co.il.
  • Piryatinsky V; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Birnberg T; Personalized & Predictive Medicine, Analytics and Big Data, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Hingaly T; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Raymond E; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Kashi R; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Amit-Romach E; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Caballero IS; Immuneering Corporation, Cambridge, MA 02412.
  • Towfic F; Immuneering Corporation, Cambridge, MA 02412.
  • Ator MA; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Rubinstein E; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Laifenfeld D; Personalized & Predictive Medicine, Analytics and Big Data, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Orbach A; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Shinar D; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Marantz Y; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Grossman I; Personalized & Predictive Medicine, Analytics and Big Data, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Knappertz V; Global Clinical Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Hayden MR; Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
  • Laufer R; Discovery & Product Development, Global Research & Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel.
Proc Natl Acad Sci U S A ; 113(41): E6145-E6152, 2016 10 11.
Article em En | MEDLINE | ID: mdl-27671624
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Hidrocarboneto Arílico / Quinolonas / Encefalomielite Autoimune Experimental Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Hidrocarboneto Arílico / Quinolonas / Encefalomielite Autoimune Experimental Idioma: En Ano de publicação: 2016 Tipo de documento: Article