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A Cyclic Tetrapeptide ("Cyclodal") and Its Mirror-Image Isomer Are Both High-Affinity µ Opioid Receptor Antagonists.
Weltrowska, Grazyna; Nguyen, Thi M-D; Chung, Nga N; Wood, JodiAnne; Ma, Xiaoyu; Guo, Jason; Wilkes, Brian C; Ge, Yang; Laferrière, André; Coderre, Terence J; Schiller, Peter W.
Afiliação
  • Weltrowska G; Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal , 110 Pine Avenue des Pins Ouest, Montreal, Quebec H2W 1R7, Canada.
  • Nguyen TM; Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal , 110 Pine Avenue des Pins Ouest, Montreal, Quebec H2W 1R7, Canada.
  • Chung NN; Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal , 110 Pine Avenue des Pins Ouest, Montreal, Quebec H2W 1R7, Canada.
  • Wood J; Center for Drug Discovery, Northeastern University , 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
  • Ma X; Center for Drug Discovery, Northeastern University , 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
  • Guo J; Center for Drug Discovery, Northeastern University , 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
  • Wilkes BC; Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal , 110 Pine Avenue des Pins Ouest, Montreal, Quebec H2W 1R7, Canada.
  • Ge Y; Anesthesia Research Unit, Department of Anesthesia, McGill University , 3655 Promenade Sir William Osler, Montreal, Quebec H3G 1Y6, Canada.
  • Laferrière A; Anesthesia Research Unit, Department of Anesthesia, McGill University , 3655 Promenade Sir William Osler, Montreal, Quebec H3G 1Y6, Canada.
  • Coderre TJ; Anesthesia Research Unit, Department of Anesthesia, McGill University , 3655 Promenade Sir William Osler, Montreal, Quebec H3G 1Y6, Canada.
  • Schiller PW; Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal , 110 Pine Avenue des Pins Ouest, Montreal, Quebec H2W 1R7, Canada.
J Med Chem ; 59(19): 9243-9254, 2016 10 13.
Article em En | MEDLINE | ID: mdl-27676089
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Receptores Opioides mu Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Receptores Opioides mu Idioma: En Ano de publicação: 2016 Tipo de documento: Article