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Inhibitors of retrograde trafficking active against ricin and Shiga toxins also protect cells from several viruses, Leishmania and Chlamydiales.
Gupta, Neetu; Noël, Romain; Goudet, Amélie; Hinsinger, Karen; Michau, Aurélien; Pons, Valérie; Abdelkafi, Hajer; Secher, Thomas; Shima, Ayaka; Shtanko, Olena; Sakurai, Yasuteru; Cojean, Sandrine; Pomel, Sébastien; Liévin-Le Moal, Vanessa; Leignel, Véronique; Herweg, Jo-Ana; Fischer, Annette; Johannes, Ludger; Harrison, Kate; Beard, Philippa M; Clayette, Pascal; Le Grand, Roger; Rayner, Jonathan O; Rudel, Thomas; Vacus, Joël; Loiseau, Philippe M; Davey, Robert A; Oswald, Eric; Cintrat, Jean-Christophe; Barbier, Julien; Gillet, Daniel.
Afiliação
  • Gupta N; Institute of Biology and Technology of Saclay (IBITECS), CEA, LabEx LERMIT, Université Paris-Saclay, F-91191, Gif Sur Yvette, France.
  • Noël R; Institute of Biology and Technology of Saclay (IBITECS), CEA, LabEx LERMIT, Université Paris-Saclay, F-91191, Gif Sur Yvette, France.
  • Goudet A; Institute of Biology and Technology of Saclay (IBITECS), CEA, LabEx LERMIT, Université Paris-Saclay, F-91191, Gif Sur Yvette, France.
  • Hinsinger K; Institute of Biology and Technology of Saclay (IBITECS), CEA, LabEx LERMIT, Université Paris-Saclay, F-91191, Gif Sur Yvette, France.
  • Michau A; Institute of Biology and Technology of Saclay (IBITECS), CEA, LabEx LERMIT, Université Paris-Saclay, F-91191, Gif Sur Yvette, France.
  • Pons V; Institute of Biology and Technology of Saclay (IBITECS), CEA, LabEx LERMIT, Université Paris-Saclay, F-91191, Gif Sur Yvette, France.
  • Abdelkafi H; Institute of Biology and Technology of Saclay (IBITECS), CEA, LabEx LERMIT, Université Paris-Saclay, F-91191, Gif Sur Yvette, France.
  • Secher T; INSERM, UMR1043, CPTP, Toulouse, France.
  • Shima A; INSERM, UMR1043, CPTP, Toulouse, France.
  • Shtanko O; Texas Biomedical Research Institute, San Antonio, TX, USA.
  • Sakurai Y; Texas Biomedical Research Institute, San Antonio, TX, USA.
  • Cojean S; Antiparasitic Chemotherapy, UMR 8076, CNRS BioCIS, LabEx LERMIT, Université Paris-Sud, Université Paris-Saclay, F-92290, Chatenay-Malabry, France.
  • Pomel S; Antiparasitic Chemotherapy, UMR 8076, CNRS BioCIS, LabEx LERMIT, Université Paris-Sud, Université Paris-Saclay, F-92290, Chatenay-Malabry, France.
  • Liévin-Le Moal V; Antiparasitic Chemotherapy, UMR 8076, CNRS BioCIS, LabEx LERMIT, Université Paris-Sud, Université Paris-Saclay, F-92290, Chatenay-Malabry, France.
  • Leignel V; DRUGABILIS (French Research Performer SME), F-92290, Chatenay-Malabry, France.
  • Herweg JA; University of Würzburg, Biocenter, Chair of Microbiology, Am Hubland, D-97074, Würzburg, Germany.
  • Fischer A; University of Würzburg, Biocenter, Chair of Microbiology, Am Hubland, D-97074, Würzburg, Germany.
  • Johannes L; Institut Curie, PSL Research University, Endocytic Trafficking and Therapeutic Delivery Group, 26 rue d'Ulm, F-75248, Paris Cedex 05, France; CNRS, UMR3666, F-75005, Paris, France; INSERM, U1143, F-75005, Paris, France.
  • Harrison K; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, EH25 9RG, United Kingdom.
  • Beard PM; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, EH25 9RG, United Kingdom; The Pirbright Institute, Ash Rd, Pirbright, Surrey GH24 0NF, United Kingdom.
  • Clayette P; ImmunoPharmacology and Biosafety Laboratory, BERTIN Pharma, CEA, F-92265, Fontenay-aux-Roses, France.
  • Le Grand R; Institute of Emerging Diseases and Innovative Therapies, CEA, U1184, Immunology of Viral Infections and Autoimmune Diseases, Infectious Disease Models and Innovative Therapies Infrastructure, F-92265, Fontenay-aux-Roses, France; INSERM, U1184, F-94276, Le Kremlin-Bicêtre, France; University of Paris
  • Rayner JO; Infectious Disease Research, Southern Research, 2000 Ninth Avenue South, Birmingham, AL 35205, USA.
  • Rudel T; University of Würzburg, Biocenter, Chair of Microbiology, Am Hubland, D-97074, Würzburg, Germany.
  • Vacus J; DRUGABILIS (French Research Performer SME), F-92290, Chatenay-Malabry, France.
  • Loiseau PM; Antiparasitic Chemotherapy, UMR 8076, CNRS BioCIS, LabEx LERMIT, Université Paris-Sud, Université Paris-Saclay, F-92290, Chatenay-Malabry, France.
  • Davey RA; Texas Biomedical Research Institute, San Antonio, TX, USA.
  • Oswald E; INSERM, UMR1043, CPTP, Toulouse, France.
  • Cintrat JC; Institute of Biology and Technology of Saclay (IBITECS), CEA, LabEx LERMIT, Université Paris-Saclay, F-91191, Gif Sur Yvette, France.
  • Barbier J; Institute of Biology and Technology of Saclay (IBITECS), CEA, LabEx LERMIT, Université Paris-Saclay, F-91191, Gif Sur Yvette, France.
  • Gillet D; Institute of Biology and Technology of Saclay (IBITECS), CEA, LabEx LERMIT, Université Paris-Saclay, F-91191, Gif Sur Yvette, France. Electronic address: Daniel.GILLET@cea.fr.
Chem Biol Interact ; 267: 96-103, 2017 Apr 01.
Article em En | MEDLINE | ID: mdl-27712998
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ricina / Tiofenos / Benzamidas / Chlamydiales / Toxinas Shiga / Ebolavirus / Leishmania Idioma: En Ano de publicação: 2017 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ricina / Tiofenos / Benzamidas / Chlamydiales / Toxinas Shiga / Ebolavirus / Leishmania Idioma: En Ano de publicação: 2017 Tipo de documento: Article