Non-celiac Gluten Sensitivity (NCGS).
J Assoc Physicians India
; 64(3): 46-55, 2016 03.
Article
em En
| MEDLINE
| ID: mdl-27731558
ABSTRACT
There has been increasing interest in the entity "Non-celiac gluten sensitivity" in recent years which was first of its in 1980s. This "re-discovered" disorder is characterized by intestinal and extra-intestinal symptoms which occur after ingestion of gluten containing food. The number of such patients who neither have celiac disease nor wheat allergy, but appear to benefit from gluten withdrawal is increasing substantially. However it still remains a controversial and its pathogenesis is not well understood. Lack of biomarkers is a major limitation making it difficult to differentiate it from other gluten related disorders. Recent studies have raised the possibility that, beside gluten and wheat amylase-trypsin inhibitors (ATI), low-fermentable, poorly-absorbed, short-chain carbohydrates can contribute to symptoms (at least those related to IBS) experienced by NCGS patients. In this paper we will focus on the manifestations of NCGS and evidence for the condition. Also areas of controversy, major advances and future trends will be discussed.
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Base de dados:
MEDLINE
Assunto principal:
Doença Celíaca
/
Hipersensibilidade a Trigo
/
Glutens
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article