Consistent quantitative gene product expression: #3. Invariance with age.
Cytometry A
; 89(11): 997-1000, 2016 11.
Article
em En
| MEDLINE
| ID: mdl-27754615
ABSTRACT
The quantitative expression of cell surface antigens and light scattering properties of five cellular reference populations in stressed bone marrow specimens were compared between pediatric and adult patients treated for acute myeloid leukemia (AML). The mean intensity of each antigen as well as the within patient and between patient variability showed striking consistency between the two different age groups. The only difference between the groups of specimens was the proportion of progenitor cells in the adult cohort averaged less than three times the proportion in the pediatric cohort. These data show that the amounts of gene products expressed on bone marrow cells are invariant with age. © 2016 The Authors. Cytometry Part A Published by Wiley Periodicals, Inc. on behalf of ISAC.
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MEDLINE
Assunto principal:
Células-Tronco Hematopoéticas
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Leucemia Mieloide Aguda
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Transcriptoma
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Máquina de Vetores de Suporte
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article