Distribution of neurotoxic esterase in certain brain regions of laboratory animals.
Indian J Physiol Pharmacol
; 33(2): 107-9, 1989.
Article
em En
| MEDLINE
| ID: mdl-2777358
ABSTRACT
Certain organophosphorous compounds caused the inhibition of 'neurotoxic esterase' present in central nervous system. The role of this enzyme is different from that of cholinesterase. The level of neurotoxic esterase in brain, corpus striatum and spinal cord of rats, mice, guineapigs and hens was measured. Maximum level of the enzyme was found in hens, followed by guineapigs, rats and mice in the order. The concentration of the enzyme was higher in corpus striatum greater than whole brain greater than spinal cord. The determination of the normal level of neurotoxic esterase may be useful in monitoring the exposure to organophosphorous compounds.
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Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Hidrolases de Éster Carboxílico
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article