[Second-line treatment for metastatic or locally advanced gastric cancer].
Zhonghua Zhong Liu Za Zhi
; 38(10): 721-724, 2016 Oct 23.
Article
em Zh
| MEDLINE
| ID: mdl-27784452
ABSTRACT
Gastric cancer is one of the major causes of cancer-related deaths. Many patients with metastatic gastric cancer after first-line chemotherapy received salvage chemotherapy in routine clinical practice. Recent phase â
¢ trials demonstrated substantial prolongation of overall survival to support this chemotherapy or targeted therapy as a second-line treatment. Both ramucirumab monotherapy and ramucirumab plus paclitaxel were approved by FDA in patients with previously treated advanced gastric or gastroesophageal junction adenocarcinoma. In addition, paclitaxel, irinotecan, or docetaxel monotherapy is also recommended for preferred regimens. This review will summarize chemotherapy or targeted therapy as a second-line treatment in advanced gastric cancer.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Gástricas
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Neoplasias Esofágicas
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Protocolos de Quimioterapia Combinada Antineoplásica
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Terapia de Salvação
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Junção Esofagogástrica
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Antineoplásicos
Idioma:
Zh
Ano de publicação:
2016
Tipo de documento:
Article