Role of Equilibrative Nucleobase Transporter 1/SLC43A3 as a Ganciclovir Transporter in the Induction of Cytotoxic Effect of Ganciclovir in a Suicide Gene Therapy with Herpes Simplex Virus Thymidine Kinase.

Furukawa, Junji; Inoue, Katsuhisa; Ohta, Kinya; Yasujima, Tomoya; Mimura, Yoshihisa; Yuasa, Hiroaki

Furukawa, Junji; Inoue, Katsuhisa; Ohta, Kinya; Yasujima, Tomoya; Mimura, Yoshihisa; Yuasa, Hiroaki.

Afiliação

Furukawa J; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya (J.F., T.Y., Y.M., H.Y.); College of Pharmacy, Kinjo Gakuin University, Nagoya (K.O.); and Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, To
Inoue K; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya (J.F., T.Y., Y.M., H.Y.); College of Pharmacy, Kinjo Gakuin University, Nagoya (K.O.); and Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, To
Ohta K; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya (J.F., T.Y., Y.M., H.Y.); College of Pharmacy, Kinjo Gakuin University, Nagoya (K.O.); and Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, To
Yasujima T; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya (J.F., T.Y., Y.M., H.Y.); College of Pharmacy, Kinjo Gakuin University, Nagoya (K.O.); and Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, To
Mimura Y; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya (J.F., T.Y., Y.M., H.Y.); College of Pharmacy, Kinjo Gakuin University, Nagoya (K.O.); and Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, To
Yuasa H; Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya (J.F., T.Y., Y.M., H.Y.); College of Pharmacy, Kinjo Gakuin University, Nagoya (K.O.); and Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, To

J Pharmacol Exp Ther ; 360(1): 59-68, 2017 Jan.

Article em En | MEDLINE | ID: mdl-27807008

Assuntos

Sistemas de Transporte de Aminoácidos/metabolismo; Apoptose/genética; Ganciclovir/metabolismo; Ganciclovir/farmacologia; Terapia Genética; Simplexvirus/enzimologia; Timidina Quinase/genética; Animais; Transporte Biológico; Linhagem Celular; Cães; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Humanos; Simplexvirus/genética

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Base de dados: MEDLINE Assunto principal: Timidina Quinase / Terapia Genética / Ganciclovir / Apoptose / Simplexvirus / Sistemas de Transporte de Aminoácidos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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