Phosphoinositide 3-kinase Î³ ties chemoattractant- and adrenergic control of microglial motility.

Schneble, Nadine; Schmidt, Caroline; Bauer, Reinhard; Müller, Jörg P; Monajembashi, Shamci; Wetzker, Reinhard

Schneble, Nadine; Schmidt, Caroline; Bauer, Reinhard; Müller, Jörg P; Monajembashi, Shamci; Wetzker, Reinhard.

Afiliação

Schneble N; Institute of Molecular Cell Biology, Center for Molecular Biomedicine (CMB), University Hospital of Jena, Hans -Knöll -Straße 2, 07745 Jena, Germany. Electronic address: Nadine.Schneble@med.uni-jena.de.
Schmidt C; Institute of Molecular Cell Biology, Center for Molecular Biomedicine (CMB), University Hospital of Jena, Hans -Knöll -Straße 2, 07745 Jena, Germany. Electronic address: Caroline.Schmidt@med.uni-jena.de.
Bauer R; Institute of Molecular Cell Biology, Center for Molecular Biomedicine (CMB), University Hospital of Jena, Hans -Knöll -Straße 2, 07745 Jena, Germany. Electronic address: Reinhard.Bauer@med.uni-jena.de.
Müller JP; Institute of Molecular Cell Biology, Center for Molecular Biomedicine (CMB), University Hospital of Jena, Hans -Knöll -Straße 2, 07745 Jena, Germany. Electronic address: Joerg.Mueller2@med.uni-jena.de.
Monajembashi S; Leibnitz Institute for Age Research, Fritz Lipmann Institute (FLI), Beutenberg-Straße 11, 07745 Jena, Germany. Electronic address: shamci@fli-leibniz.de.
Wetzker R; Institute of Molecular Cell Biology, Center for Molecular Biomedicine (CMB), University Hospital of Jena, Hans -Knöll -Straße 2, 07745 Jena, Germany. Electronic address: Reinhard.Wetzker@uni-jena.de.

Mol Cell Neurosci ; 78: 1-8, 2017 01.

Article em En | MEDLINE | ID: mdl-27825984

Assuntos

Agonistas alfa-Adrenérgicos/farmacologia; Fatores Quimiotáticos/farmacologia; Quimiotaxia; Microglia/metabolismo; Norepinefrina/farmacologia; Fosfatidilinositol 3-Quinases/metabolismo; Animais; Linhagem Celular; Células Cultivadas; Complemento C5a/farmacologia; Camundongos; Camundongos Endogâmicos C57BL; Microglia/efeitos dos fármacos; Microglia/fisiologia; Fosfatidilinositol 3-Quinases/genética

Palavras-chave

CNS; Chemotaxis; Immune system; Microglia; PI3KÎ³

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Norepinefrina / Fatores Quimiotáticos / Quimiotaxia / Microglia / Agonistas alfa-Adrenérgicos / Fosfatidilinositol 3-Quinases Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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