Pyruvate oxidase of Streptococcus pneumoniae contributes to pneumolysin release.

Bryant, Joseph C; Dabbs, Ridge C; Oswalt, Katie L; Brown, Lindsey R; Rosch, Jason W; Seo, Keun S; Donaldson, Janet R; McDaniel, Larry S; Thornton, Justin A

Bryant, Joseph C; Dabbs, Ridge C; Oswalt, Katie L; Brown, Lindsey R; Rosch, Jason W; Seo, Keun S; Donaldson, Janet R; McDaniel, Larry S; Thornton, Justin A.

Afiliação

Bryant JC; Department of Biological Sciences, Mississippi State University, 295 E Lee Blvd., Harned Hall, Rm 219, Mississippi State, MS, 39762, USA.
Dabbs RC; Department of Biological Sciences, Mississippi State University, 295 E Lee Blvd., Harned Hall, Rm 219, Mississippi State, MS, 39762, USA.
Oswalt KL; Department of Biological Sciences, Mississippi State University, 295 E Lee Blvd., Harned Hall, Rm 219, Mississippi State, MS, 39762, USA.
Brown LR; Department of Biological Sciences, Mississippi State University, 295 E Lee Blvd., Harned Hall, Rm 219, Mississippi State, MS, 39762, USA.
Rosch JW; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.
Seo KS; Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, USA.
Donaldson JR; Department of Biological Sciences, University of Southern Mississippi, Hattiesburg, MS, USA.
McDaniel LS; Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, MS, USA.
Thornton JA; Department of Biological Sciences, Mississippi State University, 295 E Lee Blvd., Harned Hall, Rm 219, Mississippi State, MS, 39762, USA. thornton@biology.msstate.edu.

BMC Microbiol ; 16(1): 271, 2016 11 09.

Article em En | MEDLINE | ID: mdl-27829373

Assuntos

Piruvato Oxidase/metabolismo; Streptococcus pneumoniae/metabolismo; Estreptolisinas/metabolismo; Autólise; Proteínas de Bactérias/genética; Proteínas de Bactérias/metabolismo; Catalase; DNA Bacteriano/genética; Células Epiteliais/microbiologia; Eritrócitos/microbiologia; Genes Bacterianos; Peróxido de Hidrogênio/metabolismo; Oxigênio; Piruvato Oxidase/genética; Deleção de Sequência; Streptococcus pneumoniae/enzimologia; Streptococcus pneumoniae/genética; Estreptolisinas/genética; Virulência

Palavras-chave

Cytotoxicity; Metabolism; Pneumococcus; Pneumolysin; Protein secretion; Streptococcus pneumoniae; Toxin; Virulence

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piruvato Oxidase / Streptococcus pneumoniae / Estreptolisinas Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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