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Pradigastat disposition in humans: in vivo and in vitro investigations.
Upthagrove, Alana; Chen, Jin; Meyers, Charles D; Kulmatycki, Kenneth; Bretz, Angela; Wang, Lai; Peng, Lana; Palamar, Safet; Lin, Melissa; Majumdar, Tapan; Tran, Phi; Einolf, Heidi J.
Afiliação
  • Upthagrove A; a Department of Drug Metabolism and Pharmacokinetics , Novartis Institutes for Biomedical Research , East Hanover , NJ , USA.
  • Chen J; a Department of Drug Metabolism and Pharmacokinetics , Novartis Institutes for Biomedical Research , East Hanover , NJ , USA.
  • Meyers CD; b Translational Medicine, Novartis Institutes for Biomedical Research , Cambridge , MA , USA.
  • Kulmatycki K; a Department of Drug Metabolism and Pharmacokinetics , Novartis Institutes for Biomedical Research , East Hanover , NJ , USA.
  • Bretz A; c The Genomics Institute of the Novartis Research Foundation, Novartis Institutes for Biomedical Research , San Diego , CA , USA , and.
  • Wang L; a Department of Drug Metabolism and Pharmacokinetics , Novartis Institutes for Biomedical Research , East Hanover , NJ , USA.
  • Peng L; a Department of Drug Metabolism and Pharmacokinetics , Novartis Institutes for Biomedical Research , East Hanover , NJ , USA.
  • Palamar S; a Department of Drug Metabolism and Pharmacokinetics , Novartis Institutes for Biomedical Research , East Hanover , NJ , USA.
  • Lin M; d Technical Research and Development, Novartis Pharmaceuticals , East Hanover , NJ , USA.
  • Majumdar T; a Department of Drug Metabolism and Pharmacokinetics , Novartis Institutes for Biomedical Research , East Hanover , NJ , USA.
  • Tran P; a Department of Drug Metabolism and Pharmacokinetics , Novartis Institutes for Biomedical Research , East Hanover , NJ , USA.
  • Einolf HJ; a Department of Drug Metabolism and Pharmacokinetics , Novartis Institutes for Biomedical Research , East Hanover , NJ , USA.
Xenobiotica ; 47(12): 1077-1089, 2017 Dec.
Article em En | MEDLINE | ID: mdl-27855567
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Diacilglicerol O-Aciltransferase / Aminopiridinas / Acetatos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Diacilglicerol O-Aciltransferase / Aminopiridinas / Acetatos Idioma: En Ano de publicação: 2017 Tipo de documento: Article