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Membrane bound modified form of clade B Env, JRCSF is suitable for immunogen design as it is efficiently cleaved and displays all the broadly neutralizing epitopes including V2 and C2 domain-dependent conformational epitopes.
Das, Supratik; Boliar, Saikat; Mitra, Nivedita; Samal, Sweety; Bansal, Manish; Koff, Wayne C; Chakrabarti, Bimal K.
Afiliação
  • Das S; THSTI-IAVI HIV Vaccine Design Program, Translational Health Science and Technology Institute, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, PO box #04, Faridabad, Haryana, 121001, India.
  • Boliar S; THSTI-IAVI HIV Vaccine Design Program, Translational Health Science and Technology Institute, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, PO box #04, Faridabad, Haryana, 121001, India.
  • Mitra N; THSTI-IAVI HIV Vaccine Design Program, Translational Health Science and Technology Institute, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, PO box #04, Faridabad, Haryana, 121001, India.
  • Samal S; THSTI-IAVI HIV Vaccine Design Program, Translational Health Science and Technology Institute, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, PO box #04, Faridabad, Haryana, 121001, India.
  • Bansal M; THSTI-IAVI HIV Vaccine Design Program, Translational Health Science and Technology Institute, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, PO box #04, Faridabad, Haryana, 121001, India.
  • Koff WC; International AIDS Vaccine Initiative, New York, NY, USA.
  • Chakrabarti BK; THSTI-IAVI HIV Vaccine Design Program, Translational Health Science and Technology Institute, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, PO box #04, Faridabad, Haryana, 121001, India. bchakrabarti@iavi.org.
Retrovirology ; 13(1): 81, 2016 Nov 21.
Article em En | MEDLINE | ID: mdl-27871328

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Proteína gp120 do Envelope de HIV / HIV-1 / Produtos do Gene env do Vírus da Imunodeficiência Humana / Anticorpos Neutralizantes / Epitopos Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Proteína gp120 do Envelope de HIV / HIV-1 / Produtos do Gene env do Vírus da Imunodeficiência Humana / Anticorpos Neutralizantes / Epitopos Idioma: En Ano de publicação: 2016 Tipo de documento: Article