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Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling.
Ugolino, Janet; Ji, Yon Ju; Conchina, Karen; Chu, Justin; Nirujogi, Raja Sekhar; Pandey, Akhilesh; Brady, Nathan R; Hamacher-Brady, Anne; Wang, Jiou.
Afiliação
  • Ugolino J; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, and Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.
  • Ji YJ; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, and Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.
  • Conchina K; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, and Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.
  • Chu J; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, and Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.
  • Nirujogi RS; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America.
  • Pandey A; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America.
  • Brady NR; Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Maryland, United States of America.
  • Hamacher-Brady A; Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Maryland, United States of America.
  • Wang J; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, and Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.
PLoS Genet ; 12(11): e1006443, 2016 Nov.
Article em En | MEDLINE | ID: mdl-27875531
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Fatores de Troca do Nucleotídeo Guanina / Expansão das Repetições de DNA / Fatores de Transcrição de Zíper de Leucina e Hélice-Alça-Hélix Básicos / Demência Frontotemporal / Serina-Treonina Quinases TOR Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Fatores de Troca do Nucleotídeo Guanina / Expansão das Repetições de DNA / Fatores de Transcrição de Zíper de Leucina e Hélice-Alça-Hélix Básicos / Demência Frontotemporal / Serina-Treonina Quinases TOR Idioma: En Ano de publicação: 2016 Tipo de documento: Article