Radiation-induced osteosarcoma of the skull base after radiation therapy in a patient with nasopharyngeal carcinoma: a case report and review of the literature.
J Med Case Rep
; 10(1): 334, 2016 Dec 01.
Article
em En
| MEDLINE
| ID: mdl-27906102
ABSTRACT
BACKGROUND:
Radiation-induced osteosarcomas are a recognized complication of radiation therapy. Owing to the fact that it is rare, publications on radiation-induced osteosarcoma of the skull base are limited to a small series and some case reports. CASE PRESENTATION We describe a rare case of a patient with a skull base radiation-induced osteosarcoma treated 11 years before with ionizing radiation for an undifferentiated carcinoma of the nasopharynx. The patient was treated with chemotherapy alone, but he died after the third cycle.CONCLUSIONS:
Radiation-induced osteosarcoma of the skull base after treatment of nasopharyngeal carcinoma is a very rare but very aggressive complication with a poor prognosis. Chemotherapy gives bad results, and regular follow-up of treated patients should be considered.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Imageamento por Ressonância Magnética
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Osteossarcoma
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Neoplasias Nasofaríngeas
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Neoplasias Induzidas por Radiação
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article