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Discovery and initial optimization of alkoxyanthranilic acid derivatives as inhibitors of HCV NS5B polymerase.
Parcella, Kyle; Nickel, Andrew; Beno, Brett R; Sheriff, Steven; Wan, Changhong; Wang, Ying-Kai; Roberts, Susan B; Meanwell, Nicholas A; Kadow, John F.
Afiliação
  • Parcella K; Bristol-Myers Squibb, Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA. Electronic address: kyle.parcella@bms.com.
  • Nickel A; Bristol-Myers Squibb, Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA.
  • Beno BR; Bristol-Myers Squibb, Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA.
  • Sheriff S; Bristol-Myers Squibb, Research and Development, PO Box 4000, Princeton, NJ 08540, USA.
  • Wan C; Bristol-Myers Squibb, Research and Development, PO Box 4000, Princeton, NJ 08540, USA.
  • Wang YK; Bristol-Myers Squibb, Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA.
  • Roberts SB; Bristol-Myers Squibb, Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA.
  • Meanwell NA; Bristol-Myers Squibb, Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA.
  • Kadow JF; Bristol-Myers Squibb, Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA.
Bioorg Med Chem Lett ; 27(2): 295-298, 2017 01 15.
Article em En | MEDLINE | ID: mdl-27908764

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas não Estruturais Virais / Inibidores Enzimáticos / Descoberta de Drogas / Ortoaminobenzoatos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas não Estruturais Virais / Inibidores Enzimáticos / Descoberta de Drogas / Ortoaminobenzoatos Idioma: En Ano de publicação: 2017 Tipo de documento: Article