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Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism.
Lebeau, Paul; Al-Hashimi, Ali; Sood, Sudesh; Lhoták, Sárka; Yu, Pei; Gyulay, Gabriel; Paré, Guillaume; Chen, S R Wayne; Trigatti, Bernardo; Prat, Annik; Seidah, Nabil G; Austin, Richard C.
Afiliação
  • Lebeau P; From the Department of Medicine, Division of Nephrology, McMaster University and St. Joseph's Hamilton Healthcare and Hamilton Centre for Kidney Research, Hamilton, Ontario L8N 4A6.
  • Al-Hashimi A; From the Department of Medicine, Division of Nephrology, McMaster University and St. Joseph's Hamilton Healthcare and Hamilton Centre for Kidney Research, Hamilton, Ontario L8N 4A6.
  • Sood S; From the Department of Medicine, Division of Nephrology, McMaster University and St. Joseph's Hamilton Healthcare and Hamilton Centre for Kidney Research, Hamilton, Ontario L8N 4A6.
  • Lhoták S; From the Department of Medicine, Division of Nephrology, McMaster University and St. Joseph's Hamilton Healthcare and Hamilton Centre for Kidney Research, Hamilton, Ontario L8N 4A6.
  • Yu P; the Thrombosis and Atherosclerosis Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario L8L 2X2.
  • Gyulay G; the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario L8S 4L8.
  • Paré G; From the Department of Medicine, Division of Nephrology, McMaster University and St. Joseph's Hamilton Healthcare and Hamilton Centre for Kidney Research, Hamilton, Ontario L8N 4A6.
  • Chen SR; the Population Health Research Institute and the Departments of Medicine, Epidemiology and Pathology, McMaster University, Hamilton, Ontario L8L 2X2.
  • Trigatti B; the Libin Cardiovascular Institute of Alberta, Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta T2N 2T9, and.
  • Prat A; the Thrombosis and Atherosclerosis Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario L8L 2X2.
  • Seidah NG; the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario L8S 4L8.
  • Austin RC; the Laboratory of Biochemical Neuroendocrinology, Clinical Research Institute of Montreal, affiliated with the University of Montreal, Montreal, Quebec H2W 1R7, Canada.
J Biol Chem ; 292(4): 1510-1523, 2017 01 27.
Article em En | MEDLINE | ID: mdl-27909053

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Enzimológica da Expressão Gênica / Cálcio / Hepatócitos / Metabolismo dos Lipídeos / Estresse do Retículo Endoplasmático / Pró-Proteína Convertase 9 Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Enzimológica da Expressão Gênica / Cálcio / Hepatócitos / Metabolismo dos Lipídeos / Estresse do Retículo Endoplasmático / Pró-Proteína Convertase 9 Idioma: En Ano de publicação: 2017 Tipo de documento: Article