NOX isoforms in the development of abdominal aortic aneurysm.

Siu, Kin Lung; Li, Qiang; Zhang, Yixuan; Guo, Jun; Youn, Ji Youn; Du, Jie; Cai, Hua

Siu, Kin Lung; Li, Qiang; Zhang, Yixuan; Guo, Jun; Youn, Ji Youn; Du, Jie; Cai, Hua.

Afiliação

Siu KL; Divisions of Molecular Medicine and Cardiology, Departments of Anesthesiology and Medicine, Cardiovascular Research Laboratories, David Geffen School of Medicine at University of California Los Angeles, 650 Charles E. Young Drive, Los Angeles, CA 90095, USA.
Li Q; Divisions of Molecular Medicine and Cardiology, Departments of Anesthesiology and Medicine, Cardiovascular Research Laboratories, David Geffen School of Medicine at University of California Los Angeles, 650 Charles E. Young Drive, Los Angeles, CA 90095, USA.
Zhang Y; Divisions of Molecular Medicine and Cardiology, Departments of Anesthesiology and Medicine, Cardiovascular Research Laboratories, David Geffen School of Medicine at University of California Los Angeles, 650 Charles E. Young Drive, Los Angeles, CA 90095, USA.
Guo J; Beijing Anzhen Hospital, Capital Medical University, The Key Laboratory of Remodeling-Related Cardiovascular Diseases, Ministry of Education, Beijing Collaborative Innovation Center for Cardiovascular Disorders, Beijing Institute of Heart, Lung & Blood Vessel Disease, Beijing 100029, China.
Youn JY; Divisions of Molecular Medicine and Cardiology, Departments of Anesthesiology and Medicine, Cardiovascular Research Laboratories, David Geffen School of Medicine at University of California Los Angeles, 650 Charles E. Young Drive, Los Angeles, CA 90095, USA.
Du J; Beijing Anzhen Hospital, Capital Medical University, The Key Laboratory of Remodeling-Related Cardiovascular Diseases, Ministry of Education, Beijing Collaborative Innovation Center for Cardiovascular Disorders, Beijing Institute of Heart, Lung & Blood Vessel Disease, Beijing 100029, China.
Cai H; Divisions of Molecular Medicine and Cardiology, Departments of Anesthesiology and Medicine, Cardiovascular Research Laboratories, David Geffen School of Medicine at University of California Los Angeles, 650 Charles E. Young Drive, Los Angeles, CA 90095, USA. Electronic address: hcai@mednet.ucla.edu.

Redox Biol ; 11: 118-125, 2017 04.

Article em En | MEDLINE | ID: mdl-27912196

Assuntos

Aneurisma da Aorta Abdominal/genética; NADPH Oxidase 4/genética; NADPH Oxidases/genética; Óxido Nítrico Sintase Tipo III/genética; Complexo Repressor Polycomb 1/genética; Angiotensina II/metabolismo; Animais; Aneurisma da Aorta Abdominal/fisiopatologia; Apolipoproteínas E/genética; Regulação da Expressão Gênica; Humanos; Camundongos; Mutação; Estresse Oxidativo/genética; Isoformas de Proteínas/genética; Superóxidos/metabolismo; Tetra-Hidrofolato Desidrogenase/deficiência; Tetra-Hidrofolato Desidrogenase/genética

Palavras-chave

Abdominal aortic aneurysms (AAA); Angiotensin II (Ang II); Dihydrofolate reductase (DHFR); Endothelial nitric oxide synthase (eNOS) uncoupling; NOX1; NOX2; NOX4; Nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase/NOX); Nitric oxide (NO); Superoxide; Tetrahydrobiopterin (H(4)B); p47phox

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aneurisma da Aorta Abdominal / NADPH Oxidases / Óxido Nítrico Sintase Tipo III / Complexo Repressor Polycomb 1 / NADPH Oxidase 4 Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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