Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients.
Rev Bras Reumatol Engl Ed
; 56(6): 515-520, 2016.
Article
em En, Pt
| MEDLINE
| ID: mdl-27914599
ABSTRACT
We evaluated the possible association between FCGR3A V/F (158) polymorphism and SLE susceptibility and clinical phenotype in 305 sequentially retrieved SLE patients and 300 healthy controls from the southeastern part of Brazil by allele-specific polymerase chain reaction. Our results showed no association between FCGR3A 158V/F alleles and susceptibility to SLE in this series of patients albeit the heterozygous genotype was strongly associated with the disease.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Receptores de IgG
/
Lúpus Eritematoso Sistêmico
Idioma:
En
/
Pt
Ano de publicação:
2016
Tipo de documento:
Article