Bioactive phenyl ether derivatives from the marine-derived fungus Aspergillus carneus.
Nat Prod Res
; 31(16): 1875-1879, 2017 Aug.
Article
em En
| MEDLINE
| ID: mdl-27917659
ABSTRACT
A new phenyl ether derivative, 3-hydroxy-5-(3-hydroxy-5-methylphenoxy)-4-methoxybenzoic acid (1), along with two known analogues, 3,4-dihydroxy-5-(3-hydroxy-5-methylphenoxy)benzoic acid (2) and 3-hydroxy-5-(3-hydroxy-5-methylphenoxy)benzoic acid (3), were isolated from the fungus Aspergillus carneus collected from South China Sea. The structure elucidation of 1 was determined based on extensive NMR and MS spectroscopic analyses. Compound 2 showed a strong antioxidant activity with an IC50 value of 19.3 µM which was close to the positive control ascorbic acid (IC50 = 15.3 µM).
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Base de dados:
MEDLINE
Assunto principal:
Éteres Fenílicos
/
Aspergillus
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article