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JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa.
Boor, Patrick P C; de Ruiter, Petra E; Asmawidjaja, Patrick S; Lubberts, Erik; van der Laan, Luc J W; Kwekkeboom, Jaap.
Afiliação
  • Boor PPC; Department of Gastroenterology and Hepatology, Erasmus MC - University Medical Centre, Rotterdam, The Netherlands. Electronic address: p.boor@erasmusmc.nl.
  • de Ruiter PE; Department of Surgery, Erasmus MC - University Medical Centre, Rotterdam, The Netherlands.
  • Asmawidjaja PS; Department of Rheumatology, Erasmus MC - University Medical Centre, Rotterdam, The Netherlands.
  • Lubberts E; Department of Rheumatology, Erasmus MC - University Medical Centre, Rotterdam, The Netherlands.
  • van der Laan LJW; Department of Surgery, Erasmus MC - University Medical Centre, Rotterdam, The Netherlands.
  • Kwekkeboom J; Department of Gastroenterology and Hepatology, Erasmus MC - University Medical Centre, Rotterdam, The Netherlands.
Transl Res ; 188: 67-79, 2017 10.
Article em En | MEDLINE | ID: mdl-27931982
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Pirimidinas / Pirróis / Células Dendríticas / Regulação da Expressão Gênica / Interferon-alfa / Inibidores de Proteínas Quinases Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Pirimidinas / Pirróis / Células Dendríticas / Regulação da Expressão Gênica / Interferon-alfa / Inibidores de Proteínas Quinases Idioma: En Ano de publicação: 2017 Tipo de documento: Article