Successful T-cell Replete Hematopoietic Stem Cell Boost Without Conditioning for Late Graft Failure.
Transplant Proc
; 48(9): 3225-3226, 2016 Nov.
Article
em En
| MEDLINE
| ID: mdl-27932187
ABSTRACT
Late graft failure is a rare but significant complication after allogeneic stem cell transplantation, which is often complicated by severe infections. We report a case of late graft failure, which was successfully treated with a T-cell replete hematopoietic stem cell boost without conditioning that induced rapid engraftment and relieved the patient of infection. Discontinuation of immunosuppressants and nilotinib administration suppressed the host cells. Achieving full donor chimerism allowed us to administer a peripheral blood stem cell boost without conditioning.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Reoperação
/
Transplante de Células-Tronco Hematopoéticas
/
Doença Enxerto-Hospedeiro
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article