Selective modulation of cortical state during spatial attention.
Science
; 354(6316): 1140-1144, 2016 12 02.
Article
em En
| MEDLINE
| ID: mdl-27934763
ABSTRACT
Neocortical activity is permeated with endogenously generated fluctuations, but how these dynamics affect goal-directed behavior remains a mystery. We found that ensemble neural activity in primate visual cortex spontaneously fluctuated between phases of vigorous (On) and faint (Off) spiking synchronously across cortical layers. These On-Off dynamics, reflecting global changes in cortical state, were also modulated at a local scale during selective attention. Moreover, the momentary phase of local ensemble activity predicted behavioral performance. Our results show that cortical state is controlled locally within a cortical map according to cognitive demands and reveal the impact of these local changes in cortical state on goal-directed behavior.
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Base de dados:
MEDLINE
Assunto principal:
Atenção
/
Córtex Visual
/
Objetivos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article