Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1.

Shao, Di; Han, Jingyan; Hou, Xiuyun; Fry, Jessica; Behring, Jessica B; Seta, Francesca; Long, Michelle T; Roy, Hemant K; Cohen, Richard A; Matsui, Reiko; Bachschmid, Markus M

Shao, Di; Han, Jingyan; Hou, Xiuyun; Fry, Jessica; Behring, Jessica B; Seta, Francesca; Long, Michelle T; Roy, Hemant K; Cohen, Richard A; Matsui, Reiko; Bachschmid, Markus M.

Afiliação

Shao D; 1 Vascular Biology Section, Whitaker Cardiovascular Institute, Boston University School of Medicine , Boston, Massachusetts.
Han J; 1 Vascular Biology Section, Whitaker Cardiovascular Institute, Boston University School of Medicine , Boston, Massachusetts.
Hou X; 1 Vascular Biology Section, Whitaker Cardiovascular Institute, Boston University School of Medicine , Boston, Massachusetts.
Fry J; 1 Vascular Biology Section, Whitaker Cardiovascular Institute, Boston University School of Medicine , Boston, Massachusetts.
Behring JB; 1 Vascular Biology Section, Whitaker Cardiovascular Institute, Boston University School of Medicine , Boston, Massachusetts.
Seta F; 1 Vascular Biology Section, Whitaker Cardiovascular Institute, Boston University School of Medicine , Boston, Massachusetts.
Long MT; 3 Division of Gastroenterology, Boston Medical Center , Boston, Massachusetts.
Roy HK; 3 Division of Gastroenterology, Boston Medical Center , Boston, Massachusetts.
Cohen RA; 1 Vascular Biology Section, Whitaker Cardiovascular Institute, Boston University School of Medicine , Boston, Massachusetts.
Matsui R; 2 Cardiovascular Proteomics Center, Boston University School of Medicine , Boston, Massachusetts.
Bachschmid MM; 1 Vascular Biology Section, Whitaker Cardiovascular Institute, Boston University School of Medicine , Boston, Massachusetts.

Antioxid Redox Signal ; 27(6): 313-327, 2017 08 20.

Article em En | MEDLINE | ID: mdl-27958883

Assuntos

Dislipidemias/patologia; Fígado Gorduroso/patologia; Glutarredoxinas/genética; Obesidade/genética; Sirtuína 1/metabolismo; Proteína de Ligação a Elemento Regulador de Esterol 1/metabolismo; Acetilação; Animais; Modelos Animais de Doenças; Dislipidemias/genética; Dislipidemias/metabolismo; Fígado Gorduroso/genética; Fígado Gorduroso/metabolismo; Técnicas de Inativação de Genes; Glutationa/metabolismo; Células Hep G2; Humanos; Metabolismo dos Lipídeos; Camundongos; Obesidade/metabolismo; Regulação para Cima

Palavras-chave

glutaredoxin; glutathione; lipids; sirtuin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dislipidemias / Proteína de Ligação a Elemento Regulador de Esterol 1 / Glutarredoxinas / Fígado Gorduroso / Sirtuína 1 / Obesidade Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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