Gold nanoparticles increases UV and thermal stability of human serum albumin.
Biointerphases
; 11(4): 04B310, 2016 12 16.
Article
em En
| MEDLINE
| ID: mdl-27984858
ABSTRACT
Ultraviolet (UV) radiation, temperature, and time can degrade proteins. Here, the authors show that gold nanoparticles significantly protect human serum albumin from denaturation when exposed to "stressing" conditions such as UV irradiation and sustained exposure in suboptimal conditions. In particular, the authors show that gold nanoparticles significantly reduce the decrease in secondary structure induced by UV irradiation or extended exposure to ambient temperature.
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Base de dados:
MEDLINE
Assunto principal:
Desnaturação Proteica
/
Temperatura
/
Raios Ultravioleta
/
Albumina Sérica
/
Nanopartículas
/
Ouro
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article