Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950.

Salla, Manohar; Butler, Mark S; Pelingon, Ruby; Kaeslin, Geraldine; Croker, Daniel E; Reid, Janet C; Baek, Jong Min; Bernhardt, Paul V; Gillam, Elizabeth M J; Cooper, Matthew A; Robertson, Avril A B.

Afiliação

Salla M; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.
Butler MS; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.
Pelingon R; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.
Kaeslin G; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.
Croker DE; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.
Reid JC; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.
Baek JM; School of Chemistry and Molecular Biosciences, The University of Queensland , Brisbane, Queensland 4072, Australia.
Bernhardt PV; School of Chemistry and Molecular Biosciences, The University of Queensland , Brisbane, Queensland 4072, Australia.
Gillam EM; School of Chemistry and Molecular Biosciences, The University of Queensland , Brisbane, Queensland 4072, Australia.
Cooper MA; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.
Robertson AA; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland 4072, Australia.