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Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina.
Karlstetter, Marcus; Kopatz, Jens; Aslanidis, Alexander; Shahraz, Anahita; Caramoy, Albert; Linnartz-Gerlach, Bettina; Lin, Yuchen; Lückoff, Anika; Fauser, Sascha; Düker, Katharina; Claude, Janine; Wang, Yiner; Ackermann, Johannes; Schmidt, Tobias; Hornung, Veit; Skerka, Christine; Langmann, Thomas; Neumann, Harald.
Afiliação
  • Karlstetter M; Laboratory for Experimental Immunology of the Eye, Department of Ophthalmology, University of Cologne, Cologne, Germany.
  • Kopatz J; Therapeutic Research Group Ophthalmology, Bayer Pharma AG, Wuppertal, Germany.
  • Aslanidis A; Institute of Reconstructive Neurobiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Shahraz A; Laboratory for Experimental Immunology of the Eye, Department of Ophthalmology, University of Cologne, Cologne, Germany.
  • Caramoy A; Institute of Reconstructive Neurobiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Linnartz-Gerlach B; Laboratory for Experimental Immunology of the Eye, Department of Ophthalmology, University of Cologne, Cologne, Germany.
  • Lin Y; Institute of Reconstructive Neurobiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Lückoff A; Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany.
  • Fauser S; Laboratory for Experimental Immunology of the Eye, Department of Ophthalmology, University of Cologne, Cologne, Germany.
  • Düker K; Laboratory for Experimental Immunology of the Eye, Department of Ophthalmology, University of Cologne, Cologne, Germany.
  • Claude J; Institute of Reconstructive Neurobiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Wang Y; Institute of Reconstructive Neurobiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Ackermann J; Institute of Reconstructive Neurobiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Schmidt T; Institute of Reconstructive Neurobiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Hornung V; Institute of Molecular Medicine, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Skerka C; Institute of Molecular Medicine, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Langmann T; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Neumann H; Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany.
EMBO Mol Med ; 9(2): 154-166, 2017 02.
Article em En | MEDLINE | ID: mdl-28003336
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fagócitos / Retina / Ácidos Siálicos / Ativação do Complemento / Neovascularização de Coroide / Fatores Imunológicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fagócitos / Retina / Ácidos Siálicos / Ativação do Complemento / Neovascularização de Coroide / Fatores Imunológicos Idioma: En Ano de publicação: 2017 Tipo de documento: Article