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Duvelisib treatment is associated with altered expression of apoptotic regulators that helps in sensitization of chronic lymphocytic leukemia cells to venetoclax (ABT-199).
Patel, V M; Balakrishnan, K; Douglas, M; Tibbitts, T; Xu, E Y; Kutok, J L; Ayers, M; Sarkar, A; Guerrieri, R; Wierda, W G; O'Brien, S; Jain, N; Stern, H M; Gandhi, V.
Afiliação
  • Patel VM; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Balakrishnan K; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Douglas M; Infinity Pharmaceuticals Inc., Cambridge, MA, USA.
  • Tibbitts T; Infinity Pharmaceuticals Inc., Cambridge, MA, USA.
  • Xu EY; Infinity Pharmaceuticals Inc., Cambridge, MA, USA.
  • Kutok JL; Infinity Pharmaceuticals Inc., Cambridge, MA, USA.
  • Ayers M; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Sarkar A; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Guerrieri R; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Wierda WG; Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • O'Brien S; Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Jain N; Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Stern HM; Infinity Pharmaceuticals Inc., Cambridge, MA, USA.
  • Gandhi V; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Leukemia ; 31(9): 1872-1881, 2017 09.
Article em En | MEDLINE | ID: mdl-28017967
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Purinas / Sulfonamidas / Leucemia Linfocítica Crônica de Células B / Compostos Bicíclicos Heterocíclicos com Pontes / Proteínas Reguladoras de Apoptose / Isoquinolinas Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Purinas / Sulfonamidas / Leucemia Linfocítica Crônica de Células B / Compostos Bicíclicos Heterocíclicos com Pontes / Proteínas Reguladoras de Apoptose / Isoquinolinas Idioma: En Ano de publicação: 2017 Tipo de documento: Article