Mechanistic differences between HIV-1 and SIV nucleocapsid proteins and cross-species HIV-1 genomic RNA recognition.

Post, Klara; Olson, Erik D; Naufer, M Nabuan; Gorelick, Robert J; Rouzina, Ioulia; Williams, Mark C; Musier-Forsyth, Karin; Levin, Judith G

Post, Klara; Olson, Erik D; Naufer, M Nabuan; Gorelick, Robert J; Rouzina, Ioulia; Williams, Mark C; Musier-Forsyth, Karin; Levin, Judith G.

Afiliação

Post K; Section on Viral Gene Regulation, Program in Genomics of Differentiation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892-2780, USA.
Olson ED; Department of Chemistry and Biochemistry, Center for Retrovirus Research, and Center for RNA Biology, The Ohio State University, Columbus, OH, 43210, USA.
Naufer MN; Department of Physics, Northeastern University, Boston, MA, 02115, USA.
Gorelick RJ; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, 21702-1201, USA.
Rouzina I; Department of Chemistry and Biochemistry, Center for Retrovirus Research, and Center for RNA Biology, The Ohio State University, Columbus, OH, 43210, USA.
Williams MC; Department of Physics, Northeastern University, Boston, MA, 02115, USA. ma.williams@northeastern.edu.
Musier-Forsyth K; Department of Chemistry and Biochemistry, Center for Retrovirus Research, and Center for RNA Biology, The Ohio State University, Columbus, OH, 43210, USA. musier-forsyth.1@osu.edu.
Levin JG; Section on Viral Gene Regulation, Program in Genomics of Differentiation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892-2780, USA. levinju@mail.nih.gov.

Retrovirology ; 13(1): 89, 2016 Dec 29.

Article em En | MEDLINE | ID: mdl-28034301

Assuntos

Genoma Viral; HIV-1/química; Proteínas do Nucleocapsídeo/química; Proteínas do Nucleocapsídeo/metabolismo; RNA Viral/genética; Vírus da Imunodeficiência Símia/química; HIV-1/genética; Humanos; Chaperonas Moleculares/química; Chaperonas Moleculares/fisiologia; Conformação de Ácido Nucleico; Proteínas do Nucleocapsídeo/genética; Ligação Proteica; Transcrição Reversa; Vírus da Imunodeficiência Símia/genética; Produtos do Gene gag do Vírus da Imunodeficiência Humana/química; Produtos do Gene gag do Vírus da Imunodeficiência Humana/genética

Palavras-chave

HIV-1; Minus-strand transfer; Nucleic acid binding; Nucleic acid chaperone activity; Nucleocapsid proteins; Psi RNA packaging signal; Reverse transcription; SIV; Single molecule DNA stretching; Small angle X-ray scattering

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Viral / HIV-1 / Vírus da Imunodeficiência Símia / Genoma Viral / Proteínas do Nucleocapsídeo Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google