A novel alphaherpesvirus associated with fatal diseases in banded Penguins.
J Gen Virol
; 98(1): 89-95, 2017 01.
Article
em En
| MEDLINE
| ID: mdl-28036249
ABSTRACT
A novel avian alphaherpesvirus, preliminarily designated sphenicid alphaherpesvirus 1 (SpAHV-1), has been independently isolated from juvenile Humboldt and African penguins (Spheniscus humboldti and Spheniscus demersus) kept in German zoos suffering from diphtheroid oropharyngitis/laryngotracheitis and necrotizing enteritis (collectively designated as penguin-diphtheria-like disease). High-throughput sequencing was used to determine the complete genome sequences of the first two SpAHV-1 isolates. SpAHV-1 comprises a class D genome with a length of about 164 kbp, a G+C content of 45.6 mol% and encodes 86 predicted ORFs. Taxonomic association of SpAHV-1 to the genus Mardivirus was supported by gene content clustering and phylogenetic analysis of herpesvirus core genes. The presented results imply that SpAHV-1 could be the primary causative agent of penguin-diphtheria-like fatal diseases in banded penguins. These results may serve as a basis for the development of diagnostic tools in order to investigate similar cases of penguin diphtheria in wild and captive penguins.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções por Herpesviridae
/
Mardivirus
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Spheniscidae
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article