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Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes.
Goodwin, Nicole C; Ding, Zhi-Ming; Harrison, Bryce A; Strobel, Eric D; Harris, Angela L; Smith, Melinda; Thompson, Andrea Y; Xiong, Wendy; Mseeh, Faika; Bruce, Debra J; Diaz, Damaris; Gopinathan, Suma; Li, Ling; O'Neill, Emily; Thiel, Mary; Wilson, Alan G E; Carson, Kenneth G; Powell, David R; Rawlins, David B.
Afiliação
  • Goodwin NC; Department of Medicinal Chemistry, Lexicon Pharmaceuticals , 110 Allen Road, Basking Ridge, New Jersey 07920, United States.
  • Harrison BA; Department of Medicinal Chemistry, Lexicon Pharmaceuticals , 110 Allen Road, Basking Ridge, New Jersey 07920, United States.
  • Strobel ED; Department of Medicinal Chemistry, Lexicon Pharmaceuticals , 110 Allen Road, Basking Ridge, New Jersey 07920, United States.
  • Carson KG; Department of Medicinal Chemistry, Lexicon Pharmaceuticals , 110 Allen Road, Basking Ridge, New Jersey 07920, United States.
  • Rawlins DB; Department of Medicinal Chemistry, Lexicon Pharmaceuticals , 110 Allen Road, Basking Ridge, New Jersey 07920, United States.
J Med Chem ; 60(2): 710-721, 2017 01 26.
Article em En | MEDLINE | ID: mdl-28045524
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilbutiratos / Tioglicosídeos / Compostos Benzidrílicos / Transportador 1 de Glucose-Sódio / Hipoglicemiantes Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilbutiratos / Tioglicosídeos / Compostos Benzidrílicos / Transportador 1 de Glucose-Sódio / Hipoglicemiantes Idioma: En Ano de publicação: 2017 Tipo de documento: Article