Energy efficiency and pulmonary artery flow after balloon pulmonary angioplasty for inoperable, chronic thromboembolic pulmonary hypertension: Analysis by phase-contrast MRI.
Eur J Radiol
; 87: 99-104, 2017 Feb.
Article
em En
| MEDLINE
| ID: mdl-28065382
ABSTRACT
PURPOSE:
The aims of this study were to propose a new quantitative method for pulmonary artery (PA) flow energetics using phase-contrast magnetic resonance imaging (PC-MRI), and to investigate how balloon pulmonary angioplasty (BPA) impacts energetics in chronic thromboembolic pulmonary hypertension (CTEPH). MATERIALS ANDMETHODS:
PC-MRI at 3-Teslar and with a flow sensitive gradient echo was used to examine energetics prior to and following BPA for 24 CTEPH patients. Stroke volume (m; ml) and mean velocity (V; mm/s) for the main pulmonary artery (PA), right PA, and left PA were calculated from a time-flow curve derived from PC-MRI. Based on the Bernoulli principle, PA energy was identified as 1/2mV2 (µj/kg), and energy loss was defined as the following equation "energy loss=main PA energy-(rt. PA energy+lt. PA energy)".RESULTS:
Right PA energy was significantly greater post-BPA than pre-BPA (61±55 vs. 32±40µj/kg). There was no difference in main PA and left PA energies. Energy loss was significantly decreased post-BPA (18±97µj/kg) than pre-BPA (79±125µj/kg). An optimal cutoff of left PA energy of 45µj/kg pre-BPA can be used to predict patients with mPAP≥30mmHg after BPA, with an area under the curve of 0.91, 78% sensitivity, and 92% specificity.CONCLUSION:
Analysis of PA energetics using phase-contrast MRI demonstrates that BPA improves energy loss in CTEPH. In addition, BPA responses can be predicted by PA energy status pre-treatment.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Artéria Pulmonar
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Embolia Pulmonar
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Imageamento por Ressonância Magnética
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Angioplastia com Balão
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Hipertensão Pulmonar
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article