First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease.
J Infect Dis
; 215(2): 171-174, 2017 Jan 15.
Article
em En
| MEDLINE
| ID: mdl-28073857
ABSTRACT
A neonate born to an Ebola virus-positive woman was diagnosed with Ebola virus infection on her first day of life. The patient was treated with monoclonal antibodies (ZMapp), a buffy coat transfusion from an Ebola survivor, and the broad-spectrum antiviral GS-5734. On day 20, a venous blood specimen tested negative for Ebola virus by quantitative reverse-transcription polymerase chain reaction. The patient was discharged in good health on day 33 of life. Further follow-up consultations showed age-appropriate weight gain and neurodevelopment at the age of 12 months. This patient is the first neonate documented to have survived congenital infection with Ebola virus.
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Base de dados:
MEDLINE
Assunto principal:
Antivirais
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Ribonucleotídeos
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Doença pelo Vírus Ebola
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Terapias em Estudo
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Alanina
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Fatores Imunológicos
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Anticorpos Monoclonais
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article