6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.

Ros, S; Flöter, J; Kaymak, I; Da Costa, C; Houddane, A; Dubuis, S; Griffiths, B; Mitter, R; Walz, S; Blake, S; Behrens, A; Brindle, K M; Zamboni, N; Rider, M H; Schulze, A

Ros, S; Flöter, J; Kaymak, I; Da Costa, C; Houddane, A; Dubuis, S; Griffiths, B; Mitter, R; Walz, S; Blake, S; Behrens, A; Brindle, K M; Zamboni, N; Rider, M H; Schulze, A.

Afiliação

Ros S; Gene Expression Analysis Laboratory, Cancer Research UK London Research Institute, London, UK.
Flöter J; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Kaymak I; Theodor-Boveri-Institute, Biocenter, Am Hubland, Würzburg, Germany.
Da Costa C; Theodor-Boveri-Institute, Biocenter, Am Hubland, Würzburg, Germany.
Houddane A; Adult Stem Cell Laboratory, The Francis Crick Institute, London, UK.
Dubuis S; Protein Phosphorylation Unit, de Duve Institute, Université Catholique de Louvain, Brussels, Belgium.
Griffiths B; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Mitter R; Gene Expression Analysis Laboratory, Cancer Research UK London Research Institute, London, UK.
Walz S; Bioinformatics and Biostatistics, The Francis Crick Institute, London, UK.
Blake S; Comprehensive Cancer Center, Core Unit Bioinformatics, Biocenter, Würzburg, Germany.
Behrens A; Adult Stem Cell Laboratory, The Francis Crick Institute, London, UK.
Brindle KM; Adult Stem Cell Laboratory, The Francis Crick Institute, London, UK.
Zamboni N; Faculty of Life Sciences and Medicine, King's College London, Guy's Campus, London, UK.
Rider MH; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Schulze A; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.

Oncogene ; 36(23): 3287-3299, 2017 06 08.

Article em En | MEDLINE | ID: mdl-28092678

Assuntos

Biomarcadores Tumorais/metabolismo; Neoplasias do Colo/patologia; Neoplasias Pulmonares/patologia; Fosfofrutoquinase-2/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Animais; Apoptose; Biomarcadores Tumorais/genética; Proliferação de Células; Neoplasias do Colo/genética; Neoplasias do Colo/metabolismo; Frutose/metabolismo; Glucose/metabolismo; Glicólise; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Masculino; Camundongos; Camundongos Knockout; Camundongos Nus; Invasividade Neoplásica; Estadiamento de Neoplasias; Oxirredução; Via de Pentose Fosfato; Fosfofrutoquinase-2/genética; Prognóstico; Taxa de Sobrevida; Células Tumorais Cultivadas; Proteína Supressora de Tumor p53/genética; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Proteína Supressora de Tumor p53 / Neoplasias do Colo / Fosfofrutoquinase-2 / Neoplasias Pulmonares Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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